A cause for celebration but not a miracle...

Dillan’s mother, Tara Clinkscale, had experienced severe difficulties with conception and carrying to full-term. The use of the ovulation-stimulating drug, Clomid, had resulted in two failed pregnancies, miscarriages occurring at weeks 6 and 8. So it is easy to see why some commentators have grasped at the word ‘miracle’ to describe Dillan’s safe arrival.

The dictionary defines a miracle as ‘a surprising and welcome event that is not explicable by natural or scientific laws’ but this is to miss the point; while Dillan’s conception and birth represented a dramatic overcoming of known risk factors, it was not a miracle but the result of a method of risk avoidance that is open to all similarly affected women but is completely within ‘natural and scientific laws’.

Perhaps surprisingly, being of African origin is a risk factor for infertility and poor pregnancy outcome, a situation worsened by obesity and increasing age. Although not generally recognized, being of African origin doubles the risk of infertility and increases the risk of perinatal death three times. Obviously no intervention can alter a person’s race or age, however knowledge of why such a predisposition occurs can assist in preventive care. As an inbuilt protection against malaria, people of African descent have a larger number of pro-inflammatory receptor making them more likely to develop chronic inflammation in response to immune activation by ‘non-self’.

Chronic inflammation is implicated in obesity, low progesterone and all aspects of infertility and poor pregnancy outcome. By removing the source of inflammation, immune activation, Tara was, with one intervention, able to reduce each risk to Dillan. Prior to conception Tara lost 26 pounds (virtually 15 percent of her body weight) as a result of reducing her insulin resistance, she increased her progesterone by controlling the concomitant expression of the pro-inflammatory cytokines TNF alpha and INF gamma, thus protecting against a failure to implant and the risk of succumbing to pre-term labor (both requiring adequate levels of progesterone).

In addition, Tara found that a chronic skin complaint and recurrent migraines (4-6 episodes a month) also cleared, both conditions being the result of chronic inflammation, too.

By addressing cause, Tara was able to avoid the use of drugs and to safely carry Dillan to term. Everyone at EPC sends their sincere congratulation to a proud mother and father and to a new life but at the same time we are anxious that Dillan’s safe passage from conception to birth is not considered as a miracle, definitely dramatic and welcome to all concerned but the result of an intervention that is available to all. Dillan’s parents have a strong Christian faith that has sustained them through the difficult times of infertility; their prayers have been answered not by a miracle but by the discovery of the cause of inflammation. Dillan is no more and certainly no less a miracle than any other child but he is the answer to prayer in a form in which all infertile couples can share; by combating chronic inflammation, Tara has had a successful pregnancy and provided protection for Dillan that will have positive implications throughout his life.

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